Article
Pathogenic variations in Germ Cell Nuclear Acidic Peptidase (GCNA) are associated with human male infertility.
European journal of human genetics : EJHG - 1 Dec 2021
Arafat Maram, Kleiman Sandra E, AbuMadighem Ali, Zeadna Atif, Levitas Eliahu, Vardi Iris Har, Barda Shimi, Lehavi Ofer, Hauser Ron, Lunenfeld Eitan, Huleihel Mahmoud, Gershoni Moran, Parvari Ruti
Abstract excerpt
Infertility affects one in six couples, half of which are caused by a male factor. Male infertility can be caused by both, qualitative and quantitative defects, leading to Oligo- astheno-terato-zoospermia (OAT; impairment in ejaculate sperm cell concentration, motility and morphology). Azoospermia defined as complete absence of sperm cells in the ejaculation. While hundreds of genes are involved in...
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