Article
RAS Mutational Status in Advanced Colorectal Adenocarcinoma Treated With Anti-angiogenics: Preliminary Experience With Liquid Biopsy.
In vivo (Athens, Greece) - 1 Jan 2000
DE Santiago Belén García, López-Gómez Miriam, Delgado-López Pedro David, Gordo Ana Jiménez, Neria Fernando, Thuissard-Vasallo Israel John, Gómez-Raposo César, Tevar Francisco Zambrana, Moreno-Rubio Juan, Hernández Alicia Martínez, Iglesias Irene, Casado Enrique
Abstract excerpt
AIM: To determinate molecular changes in the downstream epidermal growth factor receptor signaling pathway using serial liquid biopsies in patients with metastatic colorectal tumors (mCRC) under anti-angiogenic treatment. PATIENTS AND METHODS: Determination of RAS mutation in primary tissue samples from colorectal tumors was performed in the 23 patients included in the study at diagnosis using...
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