Article
Pediatric and adult dilated cardiomyopathy are distinguished by distinct biomarker profiles.
Pediatric research - 1 Jul 2022
Gropler Melanie R F, Lipshultz Steven E, Wilkinson James D, Towbin Jeffrey A, Colan Steven D, Canter Charles E, Lavine Kory J, Simpson Kathleen E
Abstract excerpt
BACKGROUND: Emerging evidence suggests that pediatric and adult dilated cardiomyopathy (DCM) represent distinct diseases. Few diagnostic tools exist for pediatric cardiologists to assess clinical status and prognosis. We hypothesized that pediatric DCM would have a unique biomarker profile compared to adult DCM and controls. METHODS: We utilized a DNA aptamer array (SOMAScan) to compare biomarker profiles between...
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