Article
Development of biomarkers to optimize pediatric patient management: what makes children different?
Biomarkers in medicine - 1 Dec 2011
Goldman Jennifer, Becker Mara L, Jones Bridgette, Clements Mark, Leeder J Steven
Abstract excerpt
Despite the frequent utilization of biomarkers in medical practice, there is a relative paucity of information regarding validated pediatric biomarkers. Frequently, biomarkers found to be efficacious in adults are extrapolated to the pediatric clinical setting without considering that the pathogenesis of many diseases is distinctly different in children, and ontogeny directly influences disease evolution and...
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