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Article

Metabolic profiling of maternal serum of women at high-risk of spontaneous preterm birth using NMR and MGWAS approach.

Bioscience reports - 30 Sept 2021

Gupta Juhi K, Care Angharad, Goodfellow Laura, Alfirevic Zarko, Lian Lu-Yun, Müller-Myhsok Bertram, Alfirevic Ana, Phelan Marie M

Abstract excerpt

Preterm birth (PTB) is a leading global cause of infant mortality. Risk factors include genetics, lifestyle choices and infection. Understanding the mechanism of PTB could aid the development of novel approaches to prevent PTB. This study aimed to investigate the metabolic biomarkers of PTB in early pregnancy and the association of significant metabolites with participant genotypes. Maternal sera collected at 16...

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Identifiers

PMID: 34402867
DOI: 10.1042/BSR20210759
PMCID: PMC8415214

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