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Article

Lifelong Exercise in Age Rats Improves Skeletal Muscle Function and MicroRNA Profile

31 Mar 2021

Abstract excerpt

PURPOSE: Lifelong exercise is known to attenuate sarcopenia (age-associated reduction in muscle mass and function); however, the underlying molecular mechanisms remain unclear. As microRNAs are widely involved in the regulation of skeletal muscle growth and development, we aimed to evaluate the effects of lifelong regular exercise on age-related alterations in muscle microRNA expression profiles as well as on...

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PMID: 34398060
DOI: 10.1249/mss.0000000000002661

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