Article
The Potential Causes of Cystic Fibrosis-Related Diabetes.
Frontiers in endocrinology - 1 Jan 2021
Coderre Lise, Debieche Lyna, Plourde Joëlle, Rabasa-Lhoret Rémi, Lesage Sylvie
Abstract excerpt
Cystic fibrosis (CF) is a genetic disease caused by mutations in the cystic fibrosis transmembrane conductance regulator gene (CFTR). Cystic fibrosis-related diabetes (CFRD) is the most common comorbidity, affecting more than 50% of adult CF patients. Despite this high prevalence, the etiology of CFRD remains incompletely understood. Studies in young CF children show pancreatic islet disorganization, abnormal...
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