Early diagnosis of Cryptococcus neoformans var. grubii meningitis using multiplex PCR assay in an immunocompetent patient.

doi:10.1016/j.jiac.2021.08.006

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Article

Early diagnosis of Cryptococcus neoformans var. grubii meningitis using multiplex PCR assay in an immunocompetent patient.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Dec 2021

Takahashi Yoshinori, Osawa Ryosuke, Kubota Yoshifumi, Fujii Motoki, Matsuda Naoya, Watanabe Naoki, Watari Tomohisa, Otsuka Yoshihito, Hosokawa Naoto

Abstract excerpt

Cryptococcosis is an invasive fungal infection that mainly affects the lungs and central nervous system. While patients with cell-mediated immunodeficiency are at high risk of developing cryptococcosis, there have been increasing reports of cryptococcosis in immunocompetent individuals with no un...

Topics

Biological Assay
Cryptococcosis
Cryptococcus neoformans
Early Diagnosis
Genotype
Humans
Male
Meningitis
Meningitis, Cryptococcal
Middle Aged
Multilocus Sequence Typing
Multiplex Polymerase Chain Reaction
Mycological Typing Techniques

Source

Open in PubMed

Identifiers

PMID: 34393039
DOI: 10.1016/j.jiac.2021.08.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34393039-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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