Molecular Markers Reveal Epidemiological Patterns and Evolutionary Histories of the Human Pathogenic Cryptococcus.

doi:10.3389/fcimb.2021.683670

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Article

Molecular Markers Reveal Epidemiological Patterns and Evolutionary Histories of the Human Pathogenic Cryptococcus.

Frontiers in cellular and infection microbiology - 1 Jan 2021

Hong Nan, Chen Min, Xu Jianping

Abstract excerpt

The human pathogenic Cryptococcus species are the main agents of fungal meningitis in humans and the causes of other diseases collectively called cryptococcosis. There are at least eight evolutionary divergent lineages among these agents, with different lineages showing different geographic and/or ecological distributions. In this review, we describe the main strain typing methods that have been used to analyze...

Topics

Amplified Fragment Length Polymorphism Analysis
Cryptococcosis
Cryptococcus gattii
Cryptococcus neoformans
Genotype
Humans
Multilocus Sequence Typing
Phylogeny

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Identifiers

PMID: 34026667
DOI: 10.3389/fcimb.2021.683670
PMCID: PMC8134695

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