Article
Immune reconstitution inflammatory syndrome in non-HIV cryptococcal meningitis: Cross-talk between pathogen and host.
Mycoses - 1 Nov 2021
Zhou Ling-Hong, Zhao Hua-Zhen, Wang Xuan, Wang Rui-Ying, Jiang Ying-Kui, Huang Li-Ping, Yip Ching-Wan, Cheng Jia-Hui, Que Chun-Xing, Zhu Li-Ping
Abstract excerpt
BACKGROUND: Cryptococcal meningitis (CM)-associated immune reconstitution inflammatory syndrome (IRIS) is associated with high mortality, the epidemiology and pathophysiology of which is poorly understood, especially in non-HIV populations. OBJECTIVES: We aim to explore the incidence, clinical risk factors, immunological profiles and potential influence of leukotriene A4 hydroxylase (LTA4H) on non-HIV CM IRIS...
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