Article
Use of hemagglutinin and neuraminidase amplicon-based high-throughput sequencing with variant analysis to detect co-infection and resolve identical consensus sequences of seasonal influenza in a university setting.
BMC infectious diseases - 13 Aug 2021
Faleye Temitope O C, Adams Deborah, Adhikari Sangeet, Sandrolini Helen, Halden Rolf U, Varsani Arvind, Scotch Matthew
Abstract excerpt
BACKGROUND: Local transmission of seasonal influenza viruses (IVs) can be difficult to resolve. Here, we study if coupling high-throughput sequencing (HTS) of hemagglutinin (HA) and neuraminidase (NA) genes with variant analysis can resolve strains from local transmission that have identical consensus genome. We analyzed 24 samples collected over four days in January 2020 at a large university in the US. We...
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