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Article

A metagenomic analysis of pandemic influenza A (2009 H1N1) infection in patients from North America.

PloS one - 18 Oct 2010

Greninger Alexander L, Chen Eunice C, Sittler Taylor, Scheinerman Alex, Roubinian Nareg, Yu Guixia, Kim Edward, Pillai Dylan R, Guyard Cyril, Mazzulli Tony, Isa Pavel, Arias Carlos F, Hackett John, Schochetman Gerald, Miller Steve, Tang Patrick, Chiu Charles Y

Abstract excerpt

Although metagenomics has been previously employed for pathogen discovery, its cost and complexity have prevented its use as a practical front-line diagnostic for unknown infectious diseases. Here we demonstrate the utility of two metagenomics-based strategies, a pan-viral microarray (Virochip) and deep sequencing, for the identification and characterization of 2009 pandemic H1N1 influenza A virus. Using...

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Identifiers

PMID: 20976137
DOI: 10.1371/journal.pone.0013381
PMCID: PMC2956640

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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