Article
ILC1s and ILC3s Exhibit Inflammatory Phenotype in Periodontal Ligament of Periodontitis Patients.
Frontiers in immunology - 1 Jan 2021
Li Changyi, Liu Jianyue, Pan Jie, Wang Yuhui, Shen Lei, Xu Yan
Abstract excerpt
Innate lymphoid cells (ILCs) are emerging as important players in inflammatory diseases. The oral mucosal barrier harbors all ILC subsets, but how these cells regulate the immune responses in periodontal ligament tissue during periodontitis remains undefined. Here, we show that total ILCs are markedly increased in periodontal ligament of periodontitis patients compared with healthy controls. Among them, ILC1s and...
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