Article
Loss of the MAF Transcription Factor in Laryngeal Squamous Cell Carcinoma.
Biomolecules - 15 Jul 2021
Janiszewska Joanna, Bodnar Magdalena, Paczkowska Julia, Ustaszewski Adam, Smialek Maciej J, Szylberg Lukasz, Marszalek Andrzej, Kiwerska Katarzyna, Grenman Reidar, Szyfter Krzysztof, Wierzbicka Malgorzata, Giefing Maciej, Jarmuz-Szymczak Malgorzata
Abstract excerpt
MAF is a transcription factor that may act either as a tumor suppressor or as an oncogene, depending on cell type. We have shown previously that the overexpressed miR-1290 influences MAF protein levels in LSCC (laryngeal squamous cell carcinoma) cell lines. In this study, we shed further light on the interaction between miR-1290 and MAF, as well as on cellular MAF protein localization in LSCC. We confirmed the...
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