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Pancreas cancer and BRCA : A critical subset of patients with improving therapeutic outcomes

5 Aug 2021

Abstract excerpt

BACKGROUND: Patients with germline/somatic BRCA1/BRCA2 mutations (g/sBRCA1/2) comprise a distinct biologic subgroup of pancreas ductal adenocarcinoma (PDAC). METHODS: Institutional databases were queried to identify patients who had PDAC with g/sBRCA1/2. Demographics, clinicopathologic details, genomic data (annotation sBRCA1/2 according to a precision oncology knowledge base for somatic mutations), zygosity, and...

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PMID: 34351646
DOI: 10.1002/cncr.33812

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