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Article

The relationship between NLRP3 rs10159239 and Vaspin rs2236242 gene variants and obstructive sleep apnea.

Upsala journal of medical sciences - 1 Jan 2021

Kerget Buğra, Kerget Ferhan, Kahraman Çiğdem Yüce, Aksakal Alperen, Araz Ömer

Abstract excerpt

BACKGROUND: In obstructive sleep apnea (OSA), recurrent upper airway obstruction and apnea/hypopnea episodes result in endothelial dysfunction, which leads to the release of many proinflammatory cytokines and reactive oxygen species (ROS). ROS induces NLRP3, a protein involved in the synthesis of interleukin (IL)-1 and IL-18; vaspin is a serine protease inhibitor that has an important role in suppressing the...

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Identifiers

PMID: 34349888
DOI: 10.48101/ujms.v126.7603
PMCID: PMC8276347

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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