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Immune and stromal scoring system associated with tumor microenvironment and prognosis: a gene-based multi-cancer analysis

3 Aug 2021

Abstract excerpt

BACKGROUND: Tumor microenvironment (TME) is associated with tumor progression and prognosis. Previous studies provided tools to estimate immune and stromal cell infiltration in TME. However, there is still a lack of single index to reflect both immune and stromal status associated with prognosis and immunotherapy responses. METHODS: A novel immune and stromal scoring system named ISTMEscore was developed. A total...

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PMID: 34344410
DOI: 10.1186/s12967-021-03002-1

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