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Article

What's a SNP between friends: The lineage of Clostridioides difficile R20291 can effect research outcomes.

Anaerobe - 1 Oct 2021

Monteford Jorge, Bilverstone Terry W, Ingle Patrick, Philip Sheryl, Kuehne Sarah A, Minton Nigel P

Abstract excerpt

Clostridioides difficile R20291 is the most studied PCR-Ribotype 027 isolate. The two predominant lineages of this hypervirulent strain, however, exhibit substantive phenotypic differences and possess genomes that differ by a small number of nucleotide changes. It is important that the source of R20291 is taken into account in research outcomes.

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Identifiers

PMID: 34343672
DOI: 10.1016/j.anaerobe.2021.102422
PMCID: PMC8556159

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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