Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic methylation variations predict the susceptibility of six chemotherapy related adverse effects and cancer development for Chinese colorectal cancer patients.

Toxicology and applied pharmacology - 15 Sept 2021

Li Mingming, Sun Xiaomeng, Yao Houshan, Chen Wei, Zhang Feng, Gao Shouhong, Zou Xun, Chen Jiani, Qiu Shi, Wei Hua, Hu Zhiqian, Chen Wansheng

Abstract excerpt

Colorectal cancer (CRC) remains a major concern with high morbidity and mortality worldwide. Despite the positive influence of chemotherapy on the decline in CRC mortality, the negative influence of chemotherapy-related adverse effects (CRAEs) caused by capecitabine (Cap) remains a challenging problem. DNA methylation alteration plays a pivotal role in gene expression regulation. Here, we aimed to screen reliable...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Agents
Share to Colorectal Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Drug-Related Side Effects and Adverse Reactions

Share to Epigenesis, Genetic

Share to Genomics

Share to Predictive Value of Tests

Share to Registries

Source

Identifiers

PMID: 34332992
DOI: 10.1016/j.taap.2021.115657

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic methylation variations predict the susceptibility of six chemotherapy related adverse effects and cancer development for Chinese colorectal cancer patients.PMID 34332992Read ↗

Epigenetically regulated gene expression profiles reveal four molecular subtypes with prognostic and therapeutic implications in colorectal cancer.Semantic proximity Read ↗

Integrative Analysis of DNA Methylation and Gene Expression Profiles Identifies Colorectal Cancer-Related Diagnostic Biomarkers.Semantic proximity Read ↗

Development and validation of epigenetic modification-related signals for the diagnosis and prognosis of colorectal cancerSemantic proximity Read ↗

Epigenetic insights in the diagnosis, prognosis, and treatment selection in CRC, an updated reviewSemantic proximity Read ↗

DNA methylation modulates epigenetic regulation in colorectal cancer diagnosis, prognosis and precision medicineSemantic proximity Read ↗

A tumor microenvironment-specific gene expression signature predicts chemotherapy resistance in colorectal cancer patientsSemantic proximity Read ↗

Combined Analysis of the Aberrant Epigenetic Alteration of Colorectal CancerSemantic proximity Read ↗

Genome-Wide Network-Based Analysis of Colorectal Cancer Identifies Novel Prognostic Factors and an Integrative Prognostic IndexSemantic proximity Read ↗

Spermine-Related DNA Hypermethylation and Elevated Expression of Genes for Collagen Formation are Susceptible Factors for Chemotherapy-Induced Hand-Foot Syndrome in Chinese Colorectal Cancer PatientsSemantic proximity Read ↗

Novel Genetic and Epigenetic Biomarkers of Prognostic and Predictive Significance in Stage II/III Colorectal CancerSemantic proximity Read ↗

Development and Validation of Epigenetic Modification-Related Signals for the Diagnosis and Prognosis of Colorectal CancerSemantic proximity Read ↗

Development of a prognostic prediction model based on damage-associated molecular pattern for colorectal cancer applying bulk RNA-seq analysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.