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Development of a prognostic prediction model based on damage-associated molecular pattern for colorectal cancer applying bulk RNA-seq analysis

16 Jul 2025

Abstract excerpt

This study aims to develop a risk model for the prognostic prediction for colorectal cancer (CRC) patients according to the phenotype related to damage-associated molecular patterns (DAMPs). The data were sourced from the Cancer Genome Atlas (TCGA) and cBioportal databases. The DAMP score was calculated based on the TCGA cohort data using the "ssGSEA" method. Differentially expressed genes (DEGs) identified by...

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PMID: 40670526
DOI: 10.1038/s41598-025-10592-z

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