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Article

Possible role of the mitochondrial genome in the pathogenesis of autosomal dominant polycystic kidney disease.

Nephrology (Carlton, Vic.) - 1 Nov 2021

Saravanabavan Sayanthooran, Rangan Gopala K

Abstract excerpt

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic renal disease in adults and is due to heterozygous germ line variants in either PKD1, PKD2 or rarely other genes. It is characterized by marked intra-familial disease variability suggesting that other genetic and/or environmental factors are involved in determining the lifetime course ADPKD. Recently, research indicates that...

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Identifiers

PMID: 34331378
DOI: 10.1111/nep.13957

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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