Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased piRNAs in Infertile Semen Are Related to Downregulation of Sperm MitoPLD Expression

13 Jul 2021

Abstract excerpt

Currently, the molecular mechanisms underlining male infertility are still poorly understood. Our previous study has demonstrated that PIWI-interacting RNAs (piRNAs) are downregulated in seminal plasma of infertile patients and can serve as molecular biomarkers for male infertility. However, the source and mechanism for the dysregulation of piRNAs remain obscure. In this study, we found that exosomes are present...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to MicroRNA in disease regulation
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34326815
DOI: 10.3389/fendo.2021.696121

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased piRNAs in Infertile Semen Are Related to Downregulation of Sperm MitoPLD ExpressionPMID 34326815Read ↗

Systematic characterization of seminal plasma piRNAs as molecular biomarkers for male infertilitySemantic proximity Read ↗

Seminal Plasma piRNA Array Analysis Identifies Possible Biomarker piRNAs for the Diagnosis of AsthenozoospermiaSemantic proximity Read ↗

Differentially expressed miRNAs and potential therapeutic targets for asthenospermiaSemantic proximity Read ↗

MicroRNAs in spermatogenesis dysfunction and male infertility: clinical phenotypes, mechanisms and potential diagnostic biomarkers.Semantic proximity Read ↗

Small RNAs, spermatogenesis, and male infertility: a decade of retrospectSemantic proximity Read ↗

Using miRNAs as diagnostic biomarkers for male infertility: opportunities and challengesSemantic proximity Read ↗

MicroRNA profiling in spermatozoa of men with unexplained asthenozoospermiaSemantic proximity Read ↗

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male InfertilitySemantic proximity Read ↗

Investigating the Role of the microRNA-34/449 Family in Male Infertility: A Critical Analysis and Review of the LiteratureSemantic proximity Read ↗

MicroRNA and piRNA Profiles in Normal Human Testis Detected by Next Generation SequencingSemantic proximity Read ↗

Altered microRNAs expression levels of sperm and seminal plasma in patients with infertile ejaculates compared with normozoospermic malesSemantic proximity Read ↗

Identification of small non-coding RNAs as sperm quality biomarkers for in vitro fertilizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.