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Article

Altered Profile of Seminal Plasma MicroRNAs in the Molecular Diagnosis of Male Infertility

21 Sept 2011

Abstract excerpt

BACKGROUND: Although microRNAs (miRNAs) play essential roles in spermatogenesis, little is known about seminal plasma miRNAs in infertile men. We investigated the profile of seminal plasma miRNAs in infertile men to identify miRNAs that are altered in infertility; we then evaluated their diagnostic value. METHODS: Seminal plasma samples were obtained from 289 infertile men and 168 age-matched fertile control...

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PMID: 21933900
DOI: 10.1373/clinchem.2011.169714

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