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Article

Arc1 and the microbiota together modulate growth and metabolic traits in Drosophila.

Development (Cambridge, England) - 1 Aug 2021

Keith Scott A, Bishop Cassandra, Fallacaro Samantha, McCartney Brooke M

Abstract excerpt

Perturbations to animal-associated microbial communities (the microbiota) have deleterious effects on various aspects of host fitness, but the molecular processes underlying these impacts are poorly understood. Here, we identify a connection between the microbiota and the neuronal factor Arc1 that affects growth and metabolism in Drosophila. We find that Arc1 exhibits tissue-specific microbiota-dependent...

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PMID: 34323271
DOI: 10.1242/dev.195222

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