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Article

HELLS serves as a poor prognostic biomarker and its downregulation reserves the malignant phenotype in pancreatic cancer.

BMC medical genomics - 27 Jul 2021

Wang Feng-Jiao, Jing Yan-Hua, Cheng Chien-Shan, Cao Zhang-Qi, Jiao Ju-Ying, Chen Zhen

Abstract excerpt

BACKGROUND: SMARCAs, belonged to SWI/SNF2 subfamilies, are critical to cellular processes due to their modulation of chromatin remodeling processes. Although SMARCAs are implicated in the tumor progression of various cancer types, our understanding of how those members affect pancreatic carcinogenesis is quite limited and improving this requires bioinformatics analysis and biology approaches. METHODS: To address...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34315468
DOI: 10.1186/s12920-021-01043-5
PMCID: PMC8314468

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