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Article

The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO.

PLoS neglected tropical diseases - 1 Jul 2021

Dutra Heverton L C, Ford Suzanne A, Allen Scott L, Bordenstein Sarah R, Chenoweth Stephen F, Bordenstein Seth R, McGraw Elizabeth A

Abstract excerpt

Wolbachia is currently at the forefront of global efforts to control arbovirus transmission from the vector Aedes aegypti. The use of Wolbachia relies on two phenotypes-cytoplasmic incompatibility (CI), conferred by cifA and cifB genes in prophage WO, and Wolbachia-mediated pathogen blocking (WMPB). These traits allow for local, self-sustaining reductions in transmission of dengue (DENV) following release of...

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Identifiers

PMID: 34314434
DOI: 10.1371/journal.pntd.0009637
PMCID: PMC8345842

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The impact of artificial selection for Wolbachia-mediated dengue virus blocking on phage WO.PMID 34314434Read ↗

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