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Mechanisms Involved in the Active Secretion of CTX-M-15 β-Lactamase by Pathogenic Escherichia coli ST131.

Antimicrobial agents and chemotherapy - 17 Sept 2021

Rangama Severine, Lidbury Ian D E A, Holden Jennifer M, Borsetto Chiara, Murphy Andrew R J, Hawkey Peter M, Wellington Elizabeth M H

Abstract excerpt

Infections caused by antimicrobial-resistant bacterial pathogens are fast becoming an important global health issue. Strains of Escherichia coli are common causal agents of urinary tract infection and can carry multiple resistance genes. This includes the gene blaCTX-M-15, which encodes an extended-spectrum beta-lactamase (ESBL). While studying antimicrobial resistance (AMR) in the environment, we isolated...

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PMID: 34310213
DOI: 10.1128/AAC.00663-21
PMCID: PMC8448145

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Mechanisms Involved in the Active Secretion of CTX-M-15 β-Lactamase by Pathogenic Escherichia coli ST131.PMID 34310213Read ↗

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