Article
The Potential Use of Ceftazidime-Avibactam Against Carbapenem Resistant Klebsiella pneumoniae Clinical Isolates Harboring Different Carbapenemase Types in a Thai University Hospital.
Drug design, development and therapy - 1 Jan 2021
Nasomsong Worapong, Nulsopapon Parnrada, Changpradub Dhitiwat, Pongchaidecha Manat, Pungcharoenkijkul Supanun, Juntanawiwat Piraporn, Simsiriporn Waristha, Santimaleeworagun Wichai
Abstract excerpt
PURPOSE: MBL and OXA-48 genes in carbapenem-resistant Enterobacterales (CRE) have emerged as a major public health problem worldwide, including Thailand. Due to the lack of susceptibility data and dosing regimens of ceftazidime-avibactam (CZA) against CRE in Thailand, especially in colistin-resistant era, we aimed to demonstrate in vitro susceptibility data of CZA and optimal dose based on Monte Carlo simulation...
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