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Are New β-Lactam/β-Lactamase Inhibitor Combinations Promising Against Carbapenem-Resistant K. pneumoniae Isolates?

24 Feb 2025

Abstract excerpt

BACKGROUND/OBJECTIVES: (CRKP) infections present a significant clinical challenge due to limited therapeutic options and high transmission potential. This study aimed to identify the resistance genes associated with carbapenemase production in CRKP isolates and evaluate the in vitro activity of ceftazidime/avibactam (CZA) and meropenem/vaborbactam (MEV), among other β-lactam/β-lactamase inhibitor combinations....

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Antibiotic Resistance in Bacteria
Antibiotics Pharmacokinetics and Efficacy
Nosocomial Infections in ICU

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40137705
DOI: 10.3390/pathogens14030220

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