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Article

Testing the biological embedding hypothesis: Is early life adversity associated with a later proinflammatory phenotype?

Development and psychopathology - 1 Nov 2016

Ehrlich Katherine B, Ross Kharah M, Chen Edith, Miller Gregory E

Abstract excerpt

Accumulating evidence suggests that the experience of early life adversity is a risk factor for a range of poor outcomes across development, including poor physical health in adulthood. The biological embedding model of early adversity (Miller, Chen, & Parker, 2011) suggests that early adversity might become embedded within immune cells known as monocytes/macrophages, programming them to be overly aggressive to...

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Identifiers

PMID: 27691981
DOI: 10.1017/S0954579416000845
PMCID: PMC5475361

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