Article
Pan2-Pan3 complex, together with Ccr4-Not complex, has a role in the cell growth on non-fermentable carbon sources.
Biochemical and biophysical research communications - 17 Sept 2021
Fujii Shiori, Duy Duong Long, Valderrama Arvin Lapiz, Takeuchi Risa, Matsuura Eri, Ito Ayaka, Irie Kaoru, Suda Yasuyuki, Mizuno Tomoaki, Irie Kenji
Abstract excerpt
There are two major deadenylase complexes, Ccr4-Not and Pan2-Pan3, which shorten the 3' poly(A) tail of mRNA and are conserved from yeast to human. We have previously shown that the Ccr4-mediated deadenylation plays the important role in gene expression regulation in the yeast stationary phase cell. In order to further understand the role of deadenylases in different growth condition, in this study we...
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