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Relating quantitative 7T MRI across cortical depths to cytoarchitectonics, gene expression and connectomics

17 Jul 2021

Abstract excerpt

Ultra-high field MRI across the depth of the cortex has the potential to provide anatomically precise biomarkers and mechanistic insights into neurodegenerative disease like Huntington's disease that show layer-selective vulnerability. Here we compare multi-parametric mapping (MPM) measures across cortical depths for a 7T 500 μm whole brain acquisition to (a) layer-specific cell measures from the von Economo...

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PMID: 34272784
DOI: 10.1002/hbm.25595

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