Article
Association of DYNC1H1 gene SNP/CNV with disease susceptibility, GCs efficacy, HRQOL, anxiety, and depression in Chinese SLE patients.
Journal of clinical laboratory analysis - 1 Aug 2021
Huang Shunwei, Zhang Tingyu, Wang Yuhua, Wang Linlin, Yan Ziye, Teng Ying, Li Zhen, Lou Qiuyue, Liu Shuang, Cai Jing, Chen Yangfan, Li Mu, Huang Hailiang, Xu Zhouzhou, Zou Yanfeng
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus is a heterogeneous autoimmune disease characterized by multi-system injuries and overproduction of autoantibodies. There are many genetic studies on SLE, but no report has considered the relationship between cytoplasmic dynein and SLE susceptibility. OBJECTIVES: Our study intends to investigate whether DYNC1H1 gene SNP/CNV is related to SLE susceptibility, GCs efficacy,...
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