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Article

Depression and Osteoporosis: A Mendelian Randomization Study.

Calcified tissue international - 1 Dec 2021

He Bin, Lyu Qiong, Yin Lifeng, Zhang Muzi, Quan Zhengxue, Ou Yunsheng

Abstract excerpt

Observational studies suggest a link between depression and osteoporosis, but these may be subject to confounding and reverse causality. In this two-sample Mendelian randomization analysis, we included the large meta-analysis of genome-wide association studies for depression among 807,553 individuals (246,363 cases and 561,190 controls) of European descent, the large meta-analysis to identify genetic variants...

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Identifiers

PMID: 34259888
DOI: 10.1007/s00223-021-00886-5
PMCID: PMC8531056

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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