Article
Association of HLA-B Gene Polymorphisms with Type 2 Diabetes in Pashtun Ethnic Population of Khyber Pakhtunkhwa, Pakistan.
Journal of diabetes research - 1 Jan 2021
Jan Asif, Saeed Muhammad, Afridi Muhammad Hussain, Khuda Fazli, Shabbir Muhammad, Khan Hamayun, Ali Sajid, Hassan Muhammad, Samiullah, Akbar Rani, Zakiullah
Abstract excerpt
Human leukocyte antigen (HLA) system is the most polymorphic and gene dense region of human DNA that has shown many disease associations. It has been further divided into HLA classes I, II, and III. Polymorphism in HLA class II genes has been reported to play an important role in the pathogenesis of type 1 diabetes (T1D). It also showed association with T2D in different ethnic populations. However, a little is...
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