Article
Childhood DNA methylation as a marker of early life rapid weight gain and subsequent overweight.
Clinical epigenetics - 12 Jan 2021
Robinson N, Brown H, Antoun Elie, Godfrey Keith M, Hanson Mark A, Lillycrop Karen A, Crozier Sarah R, Murray Robert, Pearce M S, Relton C L, Albani V, McKay J A
Abstract excerpt
BACKGROUND: High early postnatal weight gain has been associated with childhood adiposity; however, the mechanism remains unknown. DNA methylation is a hypothesised mechanism linking early life exposures and subsequent disease. However, epigenetic changes associated with high early weight gain have not previously been investigated. Our aim was to investigate the associations between early weight gain, peripheral...
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