Article
The potential roles of genetic factors in predicting ageing-related cognitive change and Alzheimer's disease.
Ageing research reviews - 1 Sept 2021
Pan Gongbu, King Anna, Wu Feitong, Simpson-Yap Steve, Woodhouse Adele, Phipps Andrew, Vickers James C
Abstract excerpt
Alzheimer's disease (AD) is a complex neurological disorder of uncertain aetiology, although substantial research has been conducted to explore important factors related to risk of onset and progression. Both lifestyle (e.g., complex mental stimulation, vascular health) and genetic factors (e.g., APOE, BDNF, PICALM, CLU, APP, PSEN1, PSEN2, and other genes) have been associated with AD risk. Despite more than...
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