Article
Profiles of Glucose Metabolism in Different Prediabetes Phenotypes, Classified by Fasting Glycemia, 2-Hour OGTT, Glycated Hemoglobin, and 1-Hour OGTT: An IMI DIRECT Study.
Diabetes - 1 Sept 2021
Tura Andrea, Grespan Eleonora, Göbl Christian S, Koivula Robert W, Franks Paul W, Pearson Ewan R, Walker Mark, Forgie Ian M, Giordano Giuseppe N, Pavo Imre, Ruetten Hartmut, Dermitzakis Emmanouil T, McCarthy Mark I, Pedersen Oluf, Schwenk Jochen M, Adamski Jerzy, De Masi Federico, Tsirigos Konstantinos D, Brunak Søren, Viñuela Ana, Mahajan Anubha, McDonald Timothy J, Kokkola Tarja, Vangipurapu Jagadish, Cederberg Henna, Laakso Markku, Rutters Femke, Elders Petra J M, Koopman Anitra D M, Beulens Joline W, Ridderstråle Martin, Hansen Tue H, Allin Kristine H, Hansen Torben, Vestergaard Henrik, Mari Andrea
Abstract excerpt
Differences in glucose metabolism among categories of prediabetes have not been systematically investigated. In this longitudinal study, participants (N = 2,111) underwent a 2-h 75-g oral glucose tolerance test (OGTT) at baseline and 48 months. HbA1c was also measured. We classified participants as having isolated prediabetes defect (impaired fasting glucose [IFG], impaired glucose tolerance [IGT], or HbA1c...
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