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Article

Fecal Metabolome Signature in the HIV-1 Elite Control Phenotype: Enrichment of Dipeptides Acts as an HIV-1 Antagonist but a Prevotella Agonist.

Journal of virology - 25 Aug 2021

Sperk Maike, Ambikan Anoop T, Ray Shilpa, Singh Kamal, Mikaeloff Flora, Diez Rafael Ceña, Narayanan Ashwathy, Vesterbacka Jan, Nowak Piotr, Sönnerborg Anders, Neogi Ujjwal

Abstract excerpt

HIV-1 elite controllers (EC) are a rare group among HIV-1-infected individuals who can naturally control viral replication for a prolonged period. Due to their heterogeneous nature, no universal mechanism could be attributed to the EC status; instead, several host and viral factors have been discussed as playing a role. In this study, we investigated the fecal metabolome and microbiome in a Swedish cohort of EC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34232744
DOI: 10.1128/JVI.00479-21
PMCID: PMC8387056

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