Article
Eruptive agminated nevi in a successfully treated Langerhans cell histiocytosis patient.
Pediatric dermatology - 1 Jul 2021
Echavarria Maria, Schoch Jennifer, Tate Jesalyn, Motaparthi Kiran, De Benedetto Anna, Reith John, Howell Diane
Abstract excerpt
A 7-year-old girl with a history of Langerhans cell histiocytosis (LCH), in remission, presented with the sudden appearance of multiple, agminated nevi. Skin biopsy revealed a benign junctional nevus, without recurrence of LCH. Subsequent immunohistochemical testing of both the skin and iliac wing biopsies demonstrated a BRAF V600E mutation. MAPK pathway mutations have been implicated in both LCH and nevogenesis.
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