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Article

Sensitivity and optimal clinicopathological features for mutation-targeted liquid biopsy in pN0M0 EGFR-mutant lung adenocarcinoma.

Journal of cancer research and clinical oncology - 1 Jun 2022

Ito Masaoki, Miyata Yoshihiro, Hirano Shoko, Irisuna Fumiko, Kushitani Kei, Kai Yuichiro, Kishi Naoto, Tsutani Yasuhiro, Takeshima Yukio, Okada Morihito

Abstract excerpt

PURPOSE: Liquid biopsy for early-stage lung cancer diagnosis is challenging, and optimal candidates' clinicopathological features are unknown. We investigated utility and clinicopathological features of optimal candidates in somatic mutation-targeted liquid biopsy using droplet digital polymerase chain reaction (ddPCR) in pN0M0 EGFR mutation-positive lung adenocarcinoma patients. METHODS: We performed EGFR...

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PMID: 34218331
DOI: 10.1007/s00432-021-03721-4

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