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Article

Detection of EGFR mutation of pulmonary adenocarcinoma in sputum using droplet digital PCR.

BMC pulmonary medicine - 23 Mar 2021

Isaka Tetsuya, Yokose Tomoyuki, Ito Hiroyuki, Nakayama Haruhiko, Miyagi Yohei, Saito Haruhiro, Masuda Munetaka

Abstract excerpt

BACKGROUND: It is still unclear whether epidermal growth factor receptor (EGFR) mutation of primary lung adenocarcinoma can be detected on sputum samples. This study aimed to examine EGFR mutations of primary lung adenocarcinoma in sputum samples using droplet digital polymerase chain reaction (ddPCR) and compare it with an EGFR mutation in surgically resected lung cancer. METHODS: Sputum was prospectively...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33757469
DOI: 10.1186/s12890-021-01468-9
PMCID: PMC7988937

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