Article
Analyzing Genetic Differences Between Sporadic Primary and Secondary/Tertiary Hyperparathyroidism by Targeted Next-Generation Panel Sequencing.
Endocrine pathology - 1 Dec 2021
Hong Yu Ah, Park Ki Cheol, Kim Bong Kyun, Lee Jina, Sun Woo Young, Sul Hae Joung, Hwang Kyung-Ah, Choi Won Jung, Chang Yoon-Kyung, Kim Suk Young, Shin Soyoung, Park Joonhong
Abstract excerpt
Secondary hyperparathyroidism (SHPT) is characterized by excessive serum parathyroid hormone levels in response to decreasing kidney function, and tertiary hyperparathyroidism (THPT) is often the result of a long-standing SHPT. To date, several genes have been associated with the pathogenesis of primary hyperparathyroidism (PHPT). However, the molecular genetic mechanisms of uremic hyperparathyroidism (HPT)...
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