Article
A Preliminary Study Showing the Impact of Genetic and Dietary Factors on GC-MS-Based Plasma Metabolome of Patients with and without PROX1-Genetic Predisposition to T2DM up to 5 Years Prior to Prediabetes Appearance.
Current issues in molecular biology - 29 Jun 2021
Mojsak Patrycja, Miniewska Katarzyna, Godlewski Adrian, Adamska-Patruno Edyta, Samczuk Paulina, Rey-Stolle Fernanda, Bauer Witold, Barbas Coral, Kretowski Adam, Ciborowski Michal
Abstract excerpt
Risk factors for type 2 diabetes mellitus (T2DM) consist of a combination of an unhealthy, imbalanced diet and genetic factors that may interact with each other. Single nucleotide polymorphism (SNP) in the prospero homeobox 1 (PROX1) gene is a strong genetic susceptibility factor for this metabolic disorder and impaired β-cell function. As the role of this gene in T2DM development remains unclear, novel...
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