Article
Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance.
PloS one - 1 Jan 2016
Matone Alice, Scott-Boyer Marie-Pier, Carayol Jerome, Fazelzadeh Parastoo, Lefebvre Gregory, Valsesia Armand, Charon Celine, Vervoort Jacques, Astrup Arne, Saris Wim H M, Morine Melissa, Hager Jörg
Abstract excerpt
BACKGROUND AND SCOPE: Weight loss success is dependent on the ability to refrain from regaining the lost weight in time. This feature was shown to be largely variable among individuals, and these differences, with their underlying molecular processes, are diverse and not completely elucidated. Altered plasma metabolites concentration could partly explain weight loss maintenance mechanisms. In the present work, a...
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