Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities.

International journal of molecular sciences - 7 Jun 2021

Liaci Carla, Camera Mattia, Caslini Giovanni, Rando Simona, Contino Salvatore, Romano Valentino, Merlo Giorgio R

Abstract excerpt

Intellectual disability (ID) is a pathological condition characterized by limited intellectual functioning and adaptive behaviors. It affects 1-3% of the worldwide population, and no pharmacological therapies are currently available. More than 1000 genes have been found mutated in ID patients pointing out that, despite the common phenotype, the genetic bases are highly heterogeneous and apparently unrelated....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytoskeleton
Share to Intellectual Disability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neurogenesis

Share to Neurons

Share to Phenotype

Share to Signal Transduction

Share to Synapses

Share to Systems Biology

Source

Open in PubMed Open full text

Identifiers

PMID: 34200511
DOI: 10.3390/ijms22116167
PMCID: PMC8201358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Neuronal Cytoskeleton in Intellectual Disability: From Systems Biology and Modeling to Therapeutic Opportunities.PMID 34200511Read ↗

Synaptic dysfunction and intellectual disability.Semantic proximity Read ↗

Much More Than a Scaffold: Cytoskeletal Proteins in Neurological Disorders.Semantic proximity Read ↗

Genetic and epigenetic networks in intellectual disabilities.Semantic proximity Read ↗

The Neglected Genes of ALS: Cytoskeletal Dynamics Impact Synaptic Degeneration in ALSSemantic proximity Read ↗

Role of cytoskeletal abnormalities in the neuropathology and pathophysiology of type I lissencephaly.Semantic proximity Read ↗

Cytoskeletal Dynamics and Molecular Motor Dysfunction in Psychiatric Disorders: Insights from Schizophrenia and Autism Spectrum DisorderSemantic proximity Read ↗

Multiple roles for the cytoskeleton in ALSSemantic proximity Read ↗

Neuronal actin cytoskeleton gain of function in the human brainSemantic proximity Read ↗

"IF-pathies": a broad spectrum of intermediate filament-associated diseases.Semantic proximity Read ↗

ARHGEF6-dependent cytoskeletal regulation underlies a conserved program of forebrain interneuron developmentSemantic proximity Read ↗

The neurobiology of X-linked intellectual disability.Semantic proximity Read ↗

Molecular and synaptic defects in intellectual disability syndromes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.