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Article

Genomewide Association Studies in Pharmacogenomics.

Clinical pharmacology and therapeutics - 1 Sept 2021

McInnes Gregory, Yee Sook Wah, Pershad Yash, Altman Russ B

Abstract excerpt

The increasing availability of genotype data linked with information about drug-response phenotypes has enabled genomewide association studies (GWAS) that uncover genetic determinants of drug response. GWAS have discovered associations between genetic variants and both drug efficacy and adverse drug reactions. Despite these successes, the design of GWAS in pharmacogenomics (PGx) faces unique challenges. In this...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34185318
DOI: 10.1002/cpt.2349
PMCID: PMC8376796

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