Article
Prognostic values of D816V KIT mutation and peri-transplant CBFB-MYH11 MRD monitoring on acute myeloid leukemia with CBFB-MYH11.
Bone marrow transplantation - 1 Nov 2021
Cho Byung-Sik, Min Gi-June, Park Sung-Soo, Park Silvia, Jeon Young-Woo, Shin Seung-Hwan, Yahng Seung-Ah, Yoon Jae-Ho, Lee Sung-Eun, Eom Ki-Seong, Kim Yoo-Jin, Lee Seok, Min Chang-Ki, Cho Seok-Goo, Kim Dong-Wook, Lee Jong Wook, Kim Myungshin, Kim Yonggoo, Kim Hee-Je
Abstract excerpt
Given the controversies in the prognostic value of KIT mutations and optimal thresholds and time points of MRD monitoring for AML with CBFB-MYH11, we retrospectively evaluated 88 patients who underwent allogeneic hematopoietic stem cell transplantation (Allo-HSCT, n = 60) or autologous HSCT (Auto-HSCT, n = 28). The D816V KIT mutation was significantly associated with post-transplant relapse, contrasting with...
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