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Article

Apigenin inhibits the growth of colorectal cancer through down-regulation of E2F1/3 by miRNA-215-5p

24 May 2021

Abstract excerpt

BACKGROUND: Apigenin (API) is a naturally occurring plant-derived flavone, which is abundantly present in common fruits and vegetables, and shows little or no toxicity of daily diet. The treatment of colorectal cancer is limited by high recurrence rate and multidrug resistance. PURPOSE: The purpose of this study was to explore the potential therapeutic effect and possible mechanisms of API on colorectal cancer...

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PMID: 34175590
DOI: 10.1016/j.phymed.2021.153603

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