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Article

The effect of statins on RyR and RyR-associated disease.

Journal of applied physiology (Bethesda, Md. : 1985) - 1 Aug 2021

Haseeb Mohsin, Thompson Paul D

Abstract excerpt

We sought to review the effects of statins on the ryanodine receptor (RyR) and on RyR-associated diseases, with an emphasis on catecholaminergic polymorphic ventricular tachycardia (CPVT). Statins can affect skeletal muscle and produce statin-associated muscle symptoms (SAMS) but have no adverse effects on cardiac muscle. These contrasting effects may be due to differences in how statins affect the skeletal...

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Source

Identifiers

PMID: 34166122
DOI: 10.1152/japplphysiol.01003.2020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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